PAI1 Proteins
(Plasminogen Activator Inhibitor 1 (SERPINE1))
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].
Recommended next Filters:
Would you like to try our new AI Search?
33 results
SERPINE1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SERPINE1
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
1 reference
SERPINE1
Origin: Mouse
Host: Human Cells
Recombinant
> 95 % as determined by SDS-PAGE
1 image
SERPINE1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
SERPINE1
Origin: Pig
Host: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
SERPINE1
Origin: Human
Host: Wheat germ
Recombinant
WB, ELISA, AP, AA
1 image
SERPINE1
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINE1
Origin: Rat
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINE1
Origin: Rat
Host: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
SERPINE1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
SERPINE1
Origin: Mouse
Host: Human Cells
Recombinant
> 95 % as determined by reducing SDS-PAGE.
SERPINE1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
SERPINE1
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
WB, SDS, Imm, PC
SERPINE1
Origin: Rhesus Monkey
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
SERPINE1
Origin: Rabbit
Host: Escherichia coli (E. coli)
Recombinant
> 97 %
WB, SDS, Imm, PC
SERPINE1
Origin: Human
Host: HEK-293 Cells
Recombinant
> 97 % as determined by reducing SDS-PAGE.
Active
SERPINE1
Origin: Mouse
Host: Escherichia coli (E. coli)
Recombinant
> 98 % pure (SDS-PAGE)
SERPINE1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 95 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD, Func, PI
Active
1 image
Latest Publications for our PAI1 Proteins
: "Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects." in: PLoS ONE, Vol. 10, Issue 2, pp. e0116883, (2015) (PubMed).: "Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits." in: American journal of respiratory cell and molecular biology, Vol. 52, Issue 4, pp. 429-37, (2015) (PubMed).
: "Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation." in: Blood, Vol. 125, Issue 8, pp. 1339-48, (2015) (PubMed).
: "A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage." in: Cellular signalling, Vol. 27, Issue 5, pp. 923-33, (2015) (PubMed).
: "Anti-tissue plasminogen activator (tPA) as an effective therapy of neonatal hypoxia-ischemia with and without inflammation." in: CNS neuroscience & therapeutics, Vol. 21, Issue 4, pp. 367-73, (2015) (PubMed).
: "The time course of resolution of adhesions during fibrinolyitic therapy in tetracycline-induced pleural injury in rabbits." in: American journal of physiology. Lung cellular and molecular physiology, pp. ajplung.00136.2015, (2015) (PubMed).
: "Inhibition of PAI-1 antiproteolytic activity against tPA by RNA aptamers." in: Nucleic acid therapeutics, Vol. 24, Issue 4, pp. 239-49, (2014) (PubMed).
: "SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence." in: Aging cell, Vol. 13, Issue 5, pp. 890-9, (2014) (PubMed).
: "Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex." in: Biochemistry, Vol. 52, Issue 27, pp. 4697-709, (2013) (PubMed).
: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).
Aliases for PAI1 Proteins
serpin family E member 1 (SERPINE1) Proteinsserpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog (serpine1.L) Proteins
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (serpine1) Proteins
serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1) Proteins
serpin family E member 1 (Serpine1) Proteins
PAI Proteins
PAI-1 Proteins
PAI1 Proteins
Pai1 Proteins
PAI1A Proteins
Pai1aa Proteins
Planh Proteins
PLANH1 Proteins
Planh1 Proteins
RATPAI1A Proteins
SERPINE1 Proteins
si:ch211-138a11.1 Proteins
Did you look for something else?
- PAGR1 Proteins
- PAG1 Proteins
- PAG1 Proteins
- PAG1 Proteins
- PAFAH2 Proteins
- PAFAH1B3 Proteins
- PAFAH1B2 Proteins
- PAF1/PD2 Proteins
- PAEP Proteins
- PADI3 Proteins
- PADI2 Proteins
- PADI1 Proteins
- PAD4 Proteins
- PACSIN3 Proteins
- PACSIN2 Proteins
- PACSIN1 Proteins
- PACS2 Proteins
- PACRG Proteins
- PABPC5 Proteins
- PAAF1 Proteins
- PAICS Proteins
- PAIP1 Proteins
- PAIP2 Proteins
- Paired Box 3 Proteins
- Paired Box Gene 2a Proteins
- Paired Related Homeobox 1 Proteins
- PAK1 Proteins
- PAK1IP1 Proteins
- PAK3 Proteins
- PAK4 Proteins
- PAK6 Proteins
- PAK7 Proteins
- PALB2 Proteins
- PALLD Proteins
- Pallidin Proteins
- PALMD Proteins
- PAMR1 Proteins
- PAN2 Proteins
- PAN3 Proteins
- Pancreatic Lipase Proteins
You are here:
