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PAI1 Proteins

(Plasminogen Activator Inhibitor 1 (SERPINE1))
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

39 results

SERPINE1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Pubmed 1 reference
Catalog No. ABIN1319636
-15% Promotion 2026
$415.41
$488.72
save $73.31 (-15 %)
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 12 Business Days
 
SERPINE1 Origin: Human Host: Mammalian Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7538477
-15% Promotion 2026
$338.64
$398.40
save $59.76 (-15 %)
Plus shipping costs $50.00
50 μg
Shipping to: United States
Delivery in 12 to 14 Business Days
 
SERPINE1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Catalog No. ABIN1319638
-15% Promotion 2026
$415.41
$488.72
save $73.31 (-15 %)
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 12 Business Days
 
SERPINE1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by SDS-PAGE
Catalog No. ABIN7320628
-15% Promotion 2026
$489.19
$575.52
save $86.33 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
 
SERPINE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7124465
-15% Promotion 2026
$513.93
$604.62
save $90.69 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SERPINE1 Origin: Pig Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7124467
-15% Promotion 2026
$575.13
$676.62
save $101.49 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SERPINE1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505422
-15% Promotion 2026
$195.43
$229.92
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100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
 
SERPINE1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN7505535
-15% Promotion 2026
$195.43
$229.92
save $34.49 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
 
SERPINE1 Origin: Rat Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Catalog No. ABIN7504500
$349.67
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 3 to 5 Business Days
 
SERPINE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7664967
-15% Promotion 2026
$513.93
$604.62
save $90.69 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
SERPINE1 Origin: Cow Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7664968
-15% Promotion 2026
$575.13
$676.62
save $101.49 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
SERPINE1 Origin: Mouse Host: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Catalog No. ABIN1691566
-15% Promotion 2026
$533.04
$627.11
save $94.07 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Will be delivered in 4 Business Days
 
SERPINE1 Origin: Mouse Host: Mammalian Cells Recombinant Greater than 95 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7704276
-15% Promotion 2026
$666.93
$784.62
save $117.69 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
SERPINE1 Origin: Monkey Host: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Catalog No. ABIN7664966
-15% Promotion 2026
$666.93
$784.62
save $117.69 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 15 to 19 Business Days
 
SERPINE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, Imm, PC
Catalog No. ABIN7390772
-15% Promotion 2026
$586.24
$689.70
save $103.46 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SERPINE1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % WB, SDS, Imm, PC
Catalog No. ABIN7390775
-15% Promotion 2026
$613.49
$721.75
save $108.26 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SERPINE1 Origin: Rhesus Monkey Host: Escherichia coli (E. coli) Recombinant > 97 % WB, SDS, Imm, PC
Catalog No. ABIN7390784
-15% Promotion 2026
$627.11
$737.78
save $110.67 (-15 %)
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 13 to 16 Business Days
 
SERPINE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 98 % pure Active
Catalog No. ABIN935739
-15% Promotion 2026
$867.14
$1,020.17
save $153.03 (-15 %)
Plus shipping costs $50.00
10 μg
Shipping to: United States
Delivery in 16 to 21 Business Days
 
SERPINE1 Origin: Human Host: HEK-293 Cells Recombinant > 97 % as determined by reducing SDS-PAGE. Active
Catalog No. ABIN7197367
-15% Promotion 2026
$883.32
$1,039.20
save $155.88 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 11 to 14 Business Days
 
SERPINE1 Origin: Human Recombinant > 95 % (SDS-PAGE)
Catalog No. ABIN1048113
-15% Promotion 2026
$1,183.96
$1,392.90
save $208.94 (-15 %)
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 5 to 6 Business Days
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Protein Interaction (PI)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cow
    • Monkey
    • Pig
    • E. coli
    • Rabbit
    • Rhesus Monkey
  • Cited in publications
  • Images available
  • Preservative free only
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • Mammalian Cells
    • Human Cells
    • Wheat germ
  • Binding Specificity
    • AA 24-402
    • AA 23-402
    • AA 1-402
    • AA 22-402
    • Transcript Variant 1
    • AA 141-389
    • AA 24-401
    • AA 349-390
    • AA 86-185
    • partial
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • His-SUMO Tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Inactive
    • Biologically Active
  • Supplier
    • antibodies-online
    • Signalway
    • Abbexa
    • CUSABIO
    • OriGene
    • ITSI-Biosciences

Latest Publications for our PAI1 Proteins

Reichel, Hessenauer, Pflieger, Rehberg, Kanse, Zahler, Krombach, Berghaus, Strieth: "Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects." in: PLoS ONE, Vol. 10, Issue 2, pp. e0116883, (2015) (PubMed).

Florova, Azghani, Karandashova, Schaefer, Koenig, Stewart-Evans, Declerck, Idell, Komissarov: "Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits." in: American journal of respiratory cell and molecular biology, Vol. 52, Issue 4, pp. 429-37, (2015) (PubMed).

Dinarvand, Hassanian, Weiler, Rezaie: "Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation." in: Blood, Vol. 125, Issue 8, pp. 1339-48, (2015) (PubMed).

Simone, Higgins, Archambeault, Higgins, Ginnan, Singer, Higgins: "A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage." in: Cellular signalling, Vol. 27, Issue 5, pp. 923-33, (2015) (PubMed).

Yang, Kuan: "Anti-tissue plasminogen activator (tPA) as an effective therapy of neonatal hypoxia-ischemia with and without inflammation." in: CNS neuroscience & therapeutics, Vol. 21, Issue 4, pp. 367-73, (2015) (PubMed).

Komissarov, Florova, Azghani, Buchanan, Bradley, Schaefer, Koenig, Idell: "The time course of resolution of adhesions during fibrinolyitic therapy in tetracycline-induced pleural injury in rabbits." in: American journal of physiology. Lung cellular and molecular physiology, pp. ajplung.00136.2015, (2015) (PubMed).

Damare, Brandal, Fortenberry: "Inhibition of PAI-1 antiproteolytic activity against tPA by RNA aptamers." in: Nucleic acid therapeutics, Vol. 24, Issue 4, pp. 239-49, (2014) (PubMed).

Wan, Gao, Zhou, Zhang, Hao, Lian, Li, Chen, Liu: "SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence." in: Aging cell, Vol. 13, Issue 5, pp. 890-9, (2014) (PubMed).

Florova, Karandashova, Declerck, Idell, Komissarov: "Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex." in: Biochemistry, Vol. 52, Issue 27, pp. 4697-709, (2013) (PubMed).

Komissarov, Florova, Azghani, Karandashova, Kurdowska, Idell: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).

Aliases for PAI1 Proteins

serpin family E member 1 (SERPINE1) Proteins
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog (serpine1.L) Proteins
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (serpine1) Proteins
serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1) Proteins
serpin family E member 1 (Serpine1) Proteins
PAI Proteins
PAI-1 Proteins
PAI1 Proteins
Pai1 Proteins
PAI1A Proteins
Pai1aa Proteins
Planh Proteins
PLANH1 Proteins
Planh1 Proteins
RATPAI1A Proteins
SERPINE1 Proteins
si:ch211-138a11.1 Proteins
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