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PAI1 Proteins

(Plasminogen Activator Inhibitor 1 (SERPINE1))
This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009].

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39 results

PAI1 Protein (AA 1-402) (His tag)
SERPINE1 Origin: Rat Host: Mammalian Cells Recombinant > 90 % Inactive
Catalog No. ABIN7669430
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
Details
Details
 
PAI1 Protein (His tag)
SERPINE1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7669432
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
Details
Details
 
PAI1 Protein (AA 24-402) (His tag)
SERPINE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % Inactive
Catalog No. ABIN7669431
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
Details
Details
 
PAI1 Protein (His tag)
SERPINE1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % Inactive
Catalog No. ABIN7669433
-15% Promotion 2026
$1,813.56
$2,133.60
save $320.04 (-15 %)
Plus shipping costs $50.00
500 μg
Shipping to: United States
Delivery in 11 to 14 Business Days
Details
Details
 
PAI1 Protein
SERPINE1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 98 % pure (SDS-PAGE)
Catalog No. ABIN573685
-15% Promotion 2026
$2,250.17
$2,647.26
save $397.09 (-15 %)
Plus shipping costs $50.00, if applicable $20.00 dry ice
0.5 mg
Shipping to: United States
Delivery in 2 to 3 Business Days
Details
Details
 
PAI1 Protein (Transcript Variant 1)
SERPINE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
Catalog No. ABIN2731826
$388.80
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
Delivery in 4 to 8 Business Days
Details
Details
 
PAI1 Protein (AA 24-401, partial) (His tag)
SERPINE1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5712768
$529.10
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Will be delivered in 11 Business Days
Details
Details
 
PAI1 Protein (AA 23-402) (His tag)
SERPINE1 Origin: Mouse Host: Yeast Recombinant > 90 % SDS
Catalog No. ABIN5713826
$661.10
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 8 to 11 Business Days
Details
Details
 
PAI1 Protein (AA 23-402) (His-SUMO Tag)
SERPINE1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710342
$663.30
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Will be delivered in 11 Business Days
Details
Details
 
PAI1 Protein (AA 24-402) (His-SUMO Tag)
SERPINE1 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5710344
$663.30
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Will be delivered in 11 Business Days
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Details
 
PAI1 Protein (Myc-DYKDDDDK Tag)
SERPINE1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731824
$1,112.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
Shipping to: United States
Will be delivered in 11 Business Days
Details
Details
 
PAI1 Protein (Transcript Variant 1) (His tag)
SERPINE1 Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731825
$480.00
Plus shipping costs $50.00, if applicable $20.00 dry ice
10 μg
Shipping to: United States
Delivery in 4 to 8 Business Days
Details
Details
 
PAI1 Protein
SERPINE1 Origin: Rabbit Host: Escherichia coli (E. coli) Recombinant WB, SDS
Catalog No. ABIN6125444
$580.46
Plus shipping costs $50.00
50 μg (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
Details
Details
 
PAI1 Protein (AA 24-402) (His tag)
SERPINE1 Origin: Rat Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7586123
$1,643.40
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 71 Business Days
Details
Details
 
PAI1 Protein (AA 24-402) (His tag)
SERPINE1 Origin: Cow Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN7586122
$1,643.40
Plus shipping costs $50.00
100 μg (More quantities available)
Shipping to: United States
Delivery in 60 to 71 Business Days
Details
Details
 
PAI1 Protein
SERPINE1 Origin: Monkey Host: Escherichia coli (E. coli) Recombinant WB, SDS
Catalog No. ABIN6382091
$2,721.06
Plus shipping costs $50.00
1 mg (More quantities available)
Shipping to: United States
Delivery in 10 to 18 Business Days
Details
Details
 
PAI1 Protein (AA 24-402) (His tag)
SERPINE1 Origin: Pig Host: Yeast Recombinant > 90 % ELISA
Catalog No. ABIN1472327
$3,649.80
Plus shipping costs $50.00
1 mg
Shipping to: United States
Delivery in 60 to 71 Business Days
Details
Details
 
PAI1 Protein
SERPINE1 Origin: E. coli Host: Escherichia coli (E. coli) Recombinant
Catalog No. ABIN2940988
$4,646.06
Plus shipping costs $50.00, if applicable $20.00 dry ice
0.5 mg
Shipping to: United States
Delivery in 10 to 16 Business Days
Details
Details
 
PAI1 Protein
SERPINE1 Origin: Human
Catalog No. ABIN1066545
$5,487.43
Plus shipping costs $50.00
1 mg (More quantities available)
Shipping to: United States
Will be delivered in 6 Business Days
Details
Details
 
  • Type Protein
    • Protein
  • Application
    • Western Blotting (WB)
    • ELISA
    • SDS-PAGE (SDS)
    • Antibody Production (AbP)
    • Immunogen (Imm)
    • Positive Control (PC)
    • Standard (STD)
    • Affinity Purification (AP)
    • Antibody Array (AA)
    • Functional Studies (Func)
    • Protein Interaction (PI)
  • Reactivity
    • Human
    • Mouse
    • Rat
    • Cow
    • Monkey
    • Pig
    • E. coli
    • Rabbit
    • Rhesus Monkey
  • Cited in publications
  • Images available
  • Preservative free only
  • Carrier free only
  • Host
    • Escherichia coli (E. coli)
    • HEK-293 Cells
    • Yeast
    • Mammalian Cells
    • Human Cells
    • Wheat germ
  • Binding Specificity
    • AA 24-402
    • AA 23-402
    • AA 1-402
    • AA 22-402
    • Transcript Variant 1
    • AA 141-389
    • AA 24-401
    • AA 349-390
    • AA 86-185
    • partial
  • Conjugate
    • His tag
    • Un-conjugated
    • GST tag
    • His-SUMO Tag
    • His-IF2DI Tag
    • Myc-DYKDDDDK Tag
  • Protein Type
    • Recombinant
  • Format
    • Lyophilized
    • Liquid
  • Biological Activity
    • Biologically Active
    • Biologically Inactive
  • Supplier
    • antibodies-online
    • Signalway
    • Abbexa
    • CUSABIO
    • OriGene
    • ITSI-Biosciences

Latest Publications for our PAI1 Proteins

Reichel, Hessenauer, Pflieger, Rehberg, Kanse, Zahler, Krombach, Berghaus, Strieth: "Components of the Plasminogen Activation System Promote Engraftment of Porous Polyethylene Biomaterial via Common and Distinct Effects." in: PLoS ONE, Vol. 10, Issue 2, pp. e0116883, (2015) (PubMed).

Florova, Azghani, Karandashova, Schaefer, Koenig, Stewart-Evans, Declerck, Idell, Komissarov: "Targeting of plasminogen activator inhibitor 1 improves fibrinolytic therapy for tetracycline-induced pleural injury in rabbits." in: American journal of respiratory cell and molecular biology, Vol. 52, Issue 4, pp. 429-37, (2015) (PubMed).

Dinarvand, Hassanian, Weiler, Rezaie: "Intraperitoneal administration of activated protein C prevents postsurgical adhesion band formation." in: Blood, Vol. 125, Issue 8, pp. 1339-48, (2015) (PubMed).

Simone, Higgins, Archambeault, Higgins, Ginnan, Singer, Higgins: "A small molecule PAI-1 functional inhibitor attenuates neointimal hyperplasia and vascular smooth muscle cell survival by promoting PAI-1 cleavage." in: Cellular signalling, Vol. 27, Issue 5, pp. 923-33, (2015) (PubMed).

Yang, Kuan: "Anti-tissue plasminogen activator (tPA) as an effective therapy of neonatal hypoxia-ischemia with and without inflammation." in: CNS neuroscience & therapeutics, Vol. 21, Issue 4, pp. 367-73, (2015) (PubMed).

Komissarov, Florova, Azghani, Buchanan, Bradley, Schaefer, Koenig, Idell: "The time course of resolution of adhesions during fibrinolyitic therapy in tetracycline-induced pleural injury in rabbits." in: American journal of physiology. Lung cellular and molecular physiology, pp. ajplung.00136.2015, (2015) (PubMed).

Damare, Brandal, Fortenberry: "Inhibition of PAI-1 antiproteolytic activity against tPA by RNA aptamers." in: Nucleic acid therapeutics, Vol. 24, Issue 4, pp. 239-49, (2014) (PubMed).

Wan, Gao, Zhou, Zhang, Hao, Lian, Li, Chen, Liu: "SIRT1-mediated epigenetic downregulation of plasminogen activator inhibitor-1 prevents vascular endothelial replicative senescence." in: Aging cell, Vol. 13, Issue 5, pp. 890-9, (2014) (PubMed).

Florova, Karandashova, Declerck, Idell, Komissarov: "Remarkable stabilization of plasminogen activator inhibitor 1 in a "molecular sandwich" complex." in: Biochemistry, Vol. 52, Issue 27, pp. 4697-709, (2013) (PubMed).

Komissarov, Florova, Azghani, Karandashova, Kurdowska, Idell: "Active ?-macroglobulin is a reservoir for urokinase after fibrinolytic therapy in rabbits with tetracycline-induced pleural injury and in human pleural fluids." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 305, Issue 10, pp. L682-92, (2013) (PubMed).

Aliases for PAI1 Proteins

serpin family E member 1 (SERPINE1) Proteins
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 L homeolog (serpine1.L) Proteins
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 (serpine1) Proteins
serine (or cysteine) peptidase inhibitor, clade E, member 1 (Serpine1) Proteins
serpin family E member 1 (Serpine1) Proteins
PAI Proteins
PAI-1 Proteins
PAI1 Proteins
Pai1 Proteins
PAI1A Proteins
Pai1aa Proteins
Planh Proteins
PLANH1 Proteins
Planh1 Proteins
RATPAI1A Proteins
SERPINE1 Proteins
si:ch211-138a11.1 Proteins

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