Single-Minded Homolog 1 (SIM1) (Middle Region) Peptide
SIM1
Reactivity: Human
Host: Synthetic
BP, IHC
Catalog No. ABIN1540885
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Single-Minded Homolog 1 (SIM1) (Middle Region) Peptide (ABIN1540885)
Target
SIM1
(Single-Minded Homolog 1 (SIM1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Immunohistochemistry (IHC)
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Protein Region
- Middle Region
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Sequence
- SSSKSKSRTS PYPQYSGFHT ERSESDHDSQ WGGSPLTDTA SPQLLDPADR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SIM1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SIM1 (Single-Minded Homolog 1 (SIM1))
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Background
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SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.
Alias Symbols: bHLHe14
Protein Size: 766 -
Molecular Weight
- 85 kDa
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Gene ID
- 6492
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NCBI Accession
- NM_005068, NP_005059
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UniProt
- P81133
Target
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