Pancreas Specific Transcription Factor, 1a (PTF1A) (N-Term) Peptide
PTF1A
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN1540933
Quick Overview for Pancreas Specific Transcription Factor, 1a (PTF1A) (N-Term) Peptide (ABIN1540933)
Target
PTF1A
(Pancreas Specific Transcription Factor, 1a (PTF1A))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- FPSPYFDEED FFTDQSSRDP LEDSDELLGD EQAEVEFLSH QLHEYCYRDG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Ptf1a Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PTF1A (Pancreas Specific Transcription Factor, 1a (PTF1A))
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Background
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Ptf1a is a transcriptional activator. It binds to the E-box consensus sequence 5'-CANNTG-3' and may play a role in early and late pancreas development and differentiation. Ptf1a plays an important role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates and may be involved in the maintenance of exocrine pancreas-specific gene expression including ELA1 and amylase. It is required for the formation of pancreatic acinar and ductal cells. and plays an important role in cerebellar development.
Alias Symbols: PTF1-p48, PTF1p48, bHLHa29
Protein Size: 324 -
Molecular Weight
- 35 kDa
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Gene ID
- 19213
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NCBI Accession
- NM_018809, NP_061279
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UniProt
- Q9QX98
Target
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