ATG7 Autophagy Related 7 (ATG7) (C-Term) Peptide
ATG7
Reactivity: Human, Rat
Host: Synthetic
BP, WB
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- Target See all ATG7 products
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
- Protein Region
- C-Term
- Origin
- Human, Rat
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- KLVINAALGF DTFVVMRHGL KKPKQQGAGD LCPSHLVAPA DLGSSLFANI
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Atg7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
- Background
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Atg7 functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. It forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. It also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3.
Alias Symbols: Apg7l
Protein Size: 698 - Molecular Weight
- 76 kDa
- Gene ID
- 312647
- NCBI Accession
- NM_001012097, NP_001012097
- UniProt
- Q641Y5
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