ATG7 Autophagy Related 7 (ATG7) (C-Term) Peptide
ATG7
Reactivity: Human, Rat
Host: Synthetic
BP, WB
Catalog No. ABIN1541265
Quick Overview for ATG7 Autophagy Related 7 (ATG7) (C-Term) Peptide (ABIN1541265)
Target
ATG7
(ATG7 Autophagy Related 7 (ATG7))
Origin
Human, Rat
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- KLVINAALGF DTFVVMRHGL KKPKQQGAGD LCPSHLVAPA DLGSSLFANI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Atg7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATG7 (ATG7 Autophagy Related 7 (ATG7))
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Background
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Atg7 functions as an E1 enzyme essential for multisubstrates such as ATG8-like proteins and ATG12. It forms intermediate conjugates with ATG8-like proteins (GABARAP, GABARAPL1, GABARAPL2 or MAP1LC3A). PE-conjugation to ATG8-like proteins is essential for autophagy. It also acts as an E1 enzyme for ATG12 conjugation to ATG5 and ATG3.
Alias Symbols: Apg7l
Protein Size: 698 -
Molecular Weight
- 76 kDa
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Gene ID
- 312647
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NCBI Accession
- NM_001012097, NP_001012097
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UniProt
- Q641Y5
Target
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