GLI Pathogenesis-Related 1 (GLIPR1) (Middle Region) Peptide
GLIPR1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN1541359
Quick Overview for GLI Pathogenesis-Related 1 (GLIPR1) (Middle Region) Peptide (ABIN1541359)
Target
GLIPR1
(GLI Pathogenesis-Related 1 (GLIPR1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SLGENIWTGS VPIFSVSSAI TNWYDEIQDY DFKTRICKKV CGHYTQVVWA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GLIPR1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GLIPR1 (GLI Pathogenesis-Related 1 (GLIPR1))
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Background
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This gene encodes a protein with similarity to both the pathogenesis-related protein (PR) superfamily and the cysteine-rich secretory protein (CRISP) family. Increased expression of this gene is associated with myelomocytic differentiation in macrophage and decreased expression of this gene through gene methylation is associated with prostate cancer. The protein has proapoptotic activities in prostate and bladder cancer cells. This gene is a member of a cluster on chromosome 12 containing two other similar genes. Alternatively spliced variants which encode different protein isoforms have been described, however, not all variants have been fully characterized.
Alias Symbols: CRISP7, GLIPR, RTVP1
Protein Size: 266 -
Molecular Weight
- 28 kDa
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Gene ID
- 11010
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NCBI Accession
- NM_006851, NP_006842
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UniProt
- P48060
Target
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