Bradykinin Receptor B1 (BDKRB1) (C-Term) Peptide
BDKRB1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN1541373
Quick Overview for Bradykinin Receptor B1 (BDKRB1) (C-Term) Peptide (ABIN1541373)
Target
BDKRB1
(Bradykinin Receptor B1 (BDKRB1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- RTREEVSRTR CGGRKDSKTT ALILTLVVAF LVCWAPYHFF AFLEFLFQVQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BDKRB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Bradykinin Receptor B1 (BDKRB1) peptide
BDKRB1 Reactivity: Human Host: Synthetic BP, Imm
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
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Background
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Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: B1BKR, B1R, BKB1R, BKR1, BRADYB1
Protein Size: 353 -
Molecular Weight
- 40 kDa
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Gene ID
- 623
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NCBI Accession
- NM_000710, NP_000701
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UniProt
- P46663
Target
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