Bradykinin Receptor B1 (BDKRB1) (C-Term) Peptide
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- Target See all BDKRB1 products
- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NFFAFTNSSL NPVIYVFVGR LFRTKVWELY KQCTPKSLAP ISSSHRKEIF
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BDKRB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
- Synonyms
- bdkrb2 Peptide, LOC100230525 Peptide, B1BKR Peptide, B1R Peptide, BKB1R Peptide, BKR1 Peptide, BRADYB1 Peptide, BKR Peptide, Bdkrb Peptide, b1bkr Peptide, bradykinin receptor B1 Peptide, bradykinin receptor, beta 1 Peptide, bdkrb1 Peptide, BDKRB1 Peptide, Bdkrb1 Peptide
- Background
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Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: B1BKR, B1R, BKB1R, BKR1, BRADYB1
Protein Interaction Partner: GNAQ,MEP1A
Protein Size: 353 - Molecular Weight
- 40 kDa
- Gene ID
- 623
- NCBI Accession
- NM_000710, NP_000701
- UniProt
- P46663
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