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Bradykinin Receptor B1 (BDKRB1) (C-Term) Peptide

BDKRB1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973796
  • Target See all BDKRB1 products
    BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
    Protein Region
    C-Term
    Origin
    Human
    Source
    • 5
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    NFFAFTNSSL NPVIYVFVGR LFRTKVWELY KQCTPKSLAP ISSSHRKEIF
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-BDKRB1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    BDKRB1 (Bradykinin Receptor B1 (BDKRB1))
    Synonyms
    bdkrb2 Peptide, LOC100230525 Peptide, B1BKR Peptide, B1R Peptide, BKB1R Peptide, BKR1 Peptide, BRADYB1 Peptide, BKR Peptide, Bdkrb Peptide, b1bkr Peptide, bradykinin receptor B1 Peptide, bradykinin receptor, beta 1 Peptide, bdkrb1 Peptide, BDKRB1 Peptide, Bdkrb1 Peptide
    Background
    Bradykinin, a 9 aa peptide, is generated in pathophysiologic conditions such as inflammation, trauma, burns, shock, and allergy. Two types of G-protein coupled receptors have been found which bind bradykinin and mediate responses to these pathophysiologic conditions. The protein encoded by this gene is one of these receptors and is synthesized de novo following tissue injury. Receptor binding leads to an increase in the cytosolic calcium ion concentration, ultimately resulting in chronic and acute inflammatory responses. Several transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: B1BKR, B1R, BKB1R, BKR1, BRADYB1

    Protein Interaction Partner: GNAQ,MEP1A

    Protein Size: 353
    Molecular Weight
    40 kDa
    Gene ID
    623
    NCBI Accession
    NM_000710, NP_000701
    UniProt
    P46663
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