Mitochondrial Calcium Uptake 1 (MICU1) (C-Term) Peptide
MICU1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MICU1 products
- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LSDHVCDVVF ALFDCDGNGE LSNKEFVSIM KQRLMRGLEK PKDMGFTRLM
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-MICU1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
- Background
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MICU1 is a key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. It may act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner. MICU1 induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
Alias Symbols: CALC, DKFZp564C246, EFHA3, FLJ12684, CBARA1
Protein Size: 278 - Molecular Weight
- 30 kDa
- Gene ID
- 10367
- NCBI Accession
- NM_001195519, NP_001182448
- UniProt
- Q9BPX6
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