Mitochondrial Calcium Uptake 1 (MICU1) (C-Term) Peptide
MICU1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN1541583
Quick Overview for Mitochondrial Calcium Uptake 1 (MICU1) (C-Term) Peptide (ABIN1541583)
Target
MICU1
(Mitochondrial Calcium Uptake 1 (MICU1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LSDHVCDVVF ALFDCDGNGE LSNKEFVSIM KQRLMRGLEK PKDMGFTRLM
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MICU1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MICU1 (Mitochondrial Calcium Uptake 1 (MICU1))
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Background
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MICU1 is a key regulator of mitochondrial calcium uptake required for calcium entry into mitochondrion. It may act as a calcium sensor via its EF-hand domains, gating the activity of a calcium channel partner. MICU1 induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
Alias Symbols: CALC, DKFZp564C246, EFHA3, FLJ12684, CBARA1
Protein Size: 278 -
Molecular Weight
- 30 kDa
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Gene ID
- 10367
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NCBI Accession
- NM_001195519, NP_001182448
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UniProt
- Q9BPX6
Target
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