Prolyl 4-Hydroxylase, alpha Polypeptide III (P4HA3) (N-Term) Peptide
Quick Overview for Prolyl 4-Hydroxylase, alpha Polypeptide III (P4HA3) (N-Term) Peptide (ABIN1541707)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- EDSTTPVANP LLAFTLIKRL QSDWRNVVHS LEASENIRAL KDGYEKVEQD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-P4HA3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeated freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- P4HA3 (Prolyl 4-Hydroxylase, alpha Polypeptide III (P4HA3))
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Background
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This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Alias Symbols: -
Protein Size: 544 -
Molecular Weight
- 60 kDa
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Gene ID
- 283208
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NCBI Accession
- NM_182904, NP_878907
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UniProt
- Q7Z4N8
Target
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