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F11 Receptor (F11R) (C-Term) Peptide

F11R Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN1542412

Quick Overview for F11 Receptor (F11R) (C-Term) Peptide (ABIN1542412)

Target

F11R (F11 Receptor (F11R))

Origin

Human

Source

  • 7
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    C-Term

    Sequence

    SNSSYVLNPT TGELVFDPLS ASDTGEYSCE ARNGYGTPMT SNAVRMEAVE

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-F11R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    F11R (F11 Receptor (F11R))

    Background

    Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

    Alias Symbols: CD321, JAM, JAM1, JAMA, JCAM, KAT, PAM-1

    Protein Interaction Partner: ASIP,CASK,CGN,CSNK2A1,F11R,F2RL2,ITGAL,MLLT4,MPDZ,PARD3,PICK1,PRKCA,PTPRB,SGTA,TJP1,CASK,MLLT4,PARD3,Pard3,SGTA,TJP1

    Protein Size: 299

    Molecular Weight

    33 kDa

    Gene ID

    50848

    NCBI Accession

    NM_016946, NP_058642

    UniProt

    Q9Y624
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