F11 Receptor (F11R) (C-Term) Peptide
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- Target See all F11R products
- F11R (F11 Receptor (F11R))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LGILVFGIWF AYSRGHFDRT KKGTSSKKVI YSQPSARSEG EFKQTSSFLV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- F11R Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- F11R (F11 Receptor (F11R))
- Synonyms
- CD321 Peptide, JAM Peptide, JAM1 Peptide, JAMA Peptide, JCAM Peptide, KAT Peptide, PAM-1 Peptide, 9130004G24 Peptide, AA638916 Peptide, ESTM33 Peptide, JAM-1 Peptide, JAM-A Peptide, Jcam Peptide, Jcam1 Peptide, Ly106 Peptide, Jam1 Peptide, F11 receptor Peptide, F11R Peptide, F11r Peptide
- Background
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Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Alias Symbols: JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1
Protein Size: 299 - Gene ID
- 50848
- NCBI Accession
- NM_016946, NP_058642
- UniProt
- Q9Y624
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