rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB) (N-Term) Peptide
ARHGDIB
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2182046
Quick Overview for rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB) (N-Term) Peptide (ABIN2182046)
Target
ARHGDIB
(rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- MTEKAPEPHV EEDDDDELDS KLNYKPPPQK SLKELQEMDK DDESLIKYKK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARHGDIB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARHGDIB (rho GDP Dissociation Inhibitor (GDI) beta (ARHGDIB))
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Background
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Members of the Rho (or ARH) protein family and other Ras-related small GTP-binding proteins are involved in diverse cellular events, including cell signaling, proliferation, cytoskeletal organization, and secretion. The GTP-binding proteins are active only in the GTP-bound state. At least 3 classes of proteins tightly regulate cycling between the GTP-bound and GDP-bound states: GTPase-activating proteins (GAPs), guanine nucleotide-releasing factors (GRFs), and GDP-dissociation inhibitors (GDIs). The GDIs, including ARHGDIB, decrease the rate of GDP dissociation from Ras-like GTPases.
Alias Symbols: D4, GDIA2, GDID4, LYGDI, Ly-GDI, RAP1GN1, RhoGDI2
Protein Size: 201 -
Molecular Weight
- 23 kDa
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Gene ID
- 397
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NCBI Accession
- NM_001175, NP_001166
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UniProt
- P52566
Target
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