Adrenoceptor alpha 1A (ADRA1A) (C-Term) Peptide
ADRA1A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2182062
Quick Overview for Adrenoceptor alpha 1A (ADRA1A) (C-Term) Peptide (ABIN2182062)
Target
alpha 1 Adrenergic Receptor (ADRA1A)
(Adrenoceptor alpha 1A (ADRA1A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LKSGLKTDKS DSEQVTLRIH RKNAPAGGSG MASAKTKTHF SVRLLKFSRE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ADRA1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- alpha 1 Adrenergic Receptor (ADRA1A) (Adrenoceptor alpha 1A (ADRA1A))
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Background
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Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.
Alias Symbols: ADRA1C, ADRA1L1, ALPHA1AAR
Protein Size: 370 -
Molecular Weight
- 40 kDa
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Gene ID
- 148
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NCBI Accession
- NM_033304, NP_150647
Target
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