Superoxide Dismutase 1, Soluble (SOD1) (C-Term) Peptide
Quick Overview for Superoxide Dismutase 1, Soluble (SOD1) (C-Term) Peptide (ABIN2182905)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- DVSIEDSVIS LSGDHCIIGR TLVVHEKADD LGKGGNEEST KTGNAGSRLA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-SOD1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SOD1 (Superoxide Dismutase 1, Soluble (SOD1))
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Background
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SOD1 binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in its gene have been implicated as causes of familial amyotrophic lateral sclerosis.
Alias Symbols: ALS, ALS1, IPOA, SOD, hSod1, homodimer
Protein Size: 154 -
Molecular Weight
- 17 kDa
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Gene ID
- 6647
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NCBI Accession
- NM_000454, NP_000445
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UniProt
- P00441
Target
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