Histone Cluster 1, H2ae (HIST1H2AE) (N-Term) Peptide
HIST1H2AE
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183081
Quick Overview for Histone Cluster 1, H2ae (HIST1H2AE) (N-Term) Peptide (ABIN2183081)
Target
HIST1H2AE
(Histone Cluster 1, H2ae (HIST1H2AE))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GKQGGKARAK AKTRSSRAGL QFPVGRVHRL LRKGNYSERV GAGAPVYLAA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-HIST1H2AE Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HIST1H2AE (Histone Cluster 1, H2ae (HIST1H2AE))
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Background
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails, instead, they contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6p22-p21.3.
Alias Symbols: H2A.1, H2A.2, H2A/a, H2AFA
Protein Size: 130 -
Molecular Weight
- 14 kDa
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Gene ID
- 3012
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NCBI Accession
- NM_021052, NP_066390
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UniProt
- P04908
Target
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