Ring Finger Protein 213 (RNF213) (N-Term) Peptide
RNF213
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183223
$160.46
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100 μg
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Quick Overview for Ring Finger Protein 213 (RNF213) (N-Term) Peptide (ABIN2183223)
Target
RNF213
(Ring Finger Protein 213 (RNF213))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- ETGNNSVQTV FQGTLAATKR WLREVFTKNM LTSSGASFTY VKEIEVWRRL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RNF213 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RNF213 (Ring Finger Protein 213 (RNF213))
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Background
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This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2,17)(p23,q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8,17)(q24,q25) translocation has been identified with the MYC gene on chromosome 8.
Alias Symbols: -
Protein Size: 1063 -
Molecular Weight
- 118 kDa
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Gene ID
- 57674
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NCBI Accession
- NM_020954, NP_066005
Target
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