Ring Finger Protein 213 (RNF213) (N-Term) Peptide
RNF213
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RNF213 products
- RNF213 (Ring Finger Protein 213 (RNF213))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ETGNNSVQTV FQGTLAATKR WLREVFTKNM LTSSGASFTY VKEIEVWRRL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RNF213 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RNF213 (Ring Finger Protein 213 (RNF213))
- Synonyms
- RNF213 Peptide, ALO17 Peptide, C17orf27 Peptide, KIAA1618 Peptide, MYMY2 Peptide, MYSTR Peptide, NET57 Peptide, RGD1308168 Peptide, 6030403J01 Peptide, D11Ertd759e Peptide, mKIAA1554 Peptide, E3 ubiquitin-protein ligase RNF213 Peptide, ring finger protein 213 Peptide, LOC509283 Peptide, LOC100626814 Peptide, RNF213 Peptide, LOC100461067 Peptide, Rnf213 Peptide
- Background
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This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2,17)(p23,q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8,17)(q24,q25) translocation has been identified with the MYC gene on chromosome 8.
Alias Symbols: -
Protein Size: 1063 - Molecular Weight
- 118 kDa
- Gene ID
- 57674
- NCBI Accession
- NM_020954, NP_066005
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