Checkpoint Kinase 1 (CHEK1) (Middle Region) Peptide
CHEK1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183247
Quick Overview for Checkpoint Kinase 1 (CHEK1) (Middle Region) Peptide (ABIN2183247)
Target
CHEK1
(Checkpoint Kinase 1 (CHEK1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SPVNSASSEE NVKYSSSQPE PRTGLSLWDT SPSYIDKLVQ GISFSQPTCP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CHEK1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CHEK1 (Checkpoint Kinase 1 (CHEK1))
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Background
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CHEK1 is a serine/threonine-protein kinase which is required for checkpoint-mediated cell cycle arrest and activation of DNA repair in response to the presence of DNA damage or unreplicated DNA. It may also negatively regulate cell cycle progression during unperturbed cell cycles.
Protein Size: 476 -
Molecular Weight
- 52 kDa
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Gene ID
- 1111
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NCBI Accession
- NP_001107593
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UniProt
- O14757
Target
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