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Mitochondrial Ribosomal Protein L2 (MRPL2) (N-Term) Peptide

MRPL2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2183470

Quick Overview for Mitochondrial Ribosomal Protein L2 (MRPL2) (N-Term) Peptide (ABIN2183470)

Target

MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))

Origin

Human

Source

Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    GGGHKQRYRM IDFLRFRPEE TKSGPFEEKV IQVRYDPCRS ADIALVAGGS

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-MRPL2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    MRPL2 (Mitochondrial Ribosomal Protein L2 (MRPL2))

    Background

    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL2 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 12q.

    Alias Symbols: MRP-L14, RPML14

    Protein Size: 305

    Molecular Weight

    33 kDa

    Gene ID

    51069

    NCBI Accession

    NM_015950, NP_057034

    UniProt

    Q5T653
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