MHC Class I Polypeptide-Related Sequence A (MICA) (Middle Region) Peptide
MICA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183541
Quick Overview for MHC Class I Polypeptide-Related Sequence A (MICA) (Middle Region) Peptide (ABIN2183541)
Target
MICA
(MHC Class I Polypeptide-Related Sequence A (MICA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- VQSGFLAEVH LDGQPFLRYD RQKCRAKPQG QWAEDVLGNK TWDRETRDLT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MICA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MICA (MHC Class I Polypeptide-Related Sequence A (MICA))
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Background
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MICA encodes the higly polymorphic MHC (HLA) class I chain-related gene A. The protein product is expressed on the cell surface, although unlike canonical class I molecules does not seem to associate with beta-2-microglobulin. It is thought that MICA functions as a stress-induced antigen that is broadly recognized by intestinal epithelial gamma delta T cells. Alternative splicing results in multiple transcript variants.
Alias Symbols: MIC-A, PERB11.1
Protein Size: 332 -
Molecular Weight
- 36 kDa
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Gene ID
- 100507436
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NCBI Accession
- NM_001177519, NP_001170990
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UniProt
- Q96QC4
Target
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