Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (C-Term) Peptide
POLRMT
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183684
Quick Overview for Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT) (C-Term) Peptide (ABIN2183684)
Target
POLRMT
(Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- ALGRDSVGAA SVNLEPSDVP QDVYSGVAAQ VEVFRRQDAQ RGMRVAQVLE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-POLRMT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- POLRMT (Polymerase (RNA) Mitochondrial (DNA Directed) (POLRMT))
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Background
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This gene encodes a mitochondrial DNA-directed RNA polymerase. The gene product is responsible for mitochondrial gene expression as well as for providing RNA primers for initiation of replication of the mitochondrial genome. Although this polypeptide has the same function as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of phage and mitochondrial polymerases of lower eukaryotes.
Alias Symbols: APOLMT, MTRNAP, MTRPOL, h-mtRPOL
Protein Size: 1230 -
Molecular Weight
- 135 kDa
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Gene ID
- 5442
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NCBI Accession
- NM_005035, NP_005026
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UniProt
- O00411
Target
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