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Kininogen 1 (KNG1) (N-Term) Peptide

KNG1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2183947

Quick Overview for Kininogen 1 (KNG1) (N-Term) Peptide (ABIN2183947)

Target

KNG1 (Kininogen 1 (KNG1))

Origin

Human

Source

  • 10
Synthetic

Application

Blocking Peptide (BP), Western Blotting (WB)
  • Protein Region

    N-Term

    Sequence

    ALKKYNSQNQ SNNQFVLYRI TEATKTVGSD TFYSFKYEIK EGDCPVQSGK

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-KNG1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeat freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    KNG1 (Kininogen 1 (KNG1))

    Background

    Kininogens are inhibitors of thiol proteases. HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII and inhibits the thrombin- and plasmin-induced aggregation of thrombocytes. The active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects such as influence in smooth muscle contraction, induction of hypotension, natriuresis and diuresis, etc.

    Alias Symbols: BDK, KNG

    Protein Size: 391

    Molecular Weight

    43 kDa

    Gene ID

    3827

    NCBI Accession

    NM_001166451, NP_001159923

    UniProt

    C9JEX1
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