Cyclin-Dependent Kinase 7 (CDK7) (N-Term) Peptide
CDK7
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CDK7 products
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VKSRAKRYEK LDFLGEGQFA TVYKARDKNT NQIVAIKKIK LGHRSEAKDG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDK7 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
- Background
-
CDK7 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle.
Alias Symbols: CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
Protein Size: 346 - Molecular Weight
- 39 kDa
- Gene ID
- 1022
- NCBI Accession
- NM_001799, NP_001790
- UniProt
- P50613
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