Corticotropin Releasing Hormone (CRH) (C-Term) Peptide
Quick Overview for Corticotropin Releasing Hormone (CRH) (C-Term) Peptide (ABIN2184150)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CRH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Corticotropin Releasing Hormone (CRH) peptide (Ovalbumin)
CRH Reactivity: Rat Host: Synthetic WB, Imm, SDS
Corticotropin Releasing Hormone (CRH) peptide (Ovalbumin)CRH Reactivity: Mouse Host: Synthetic WB, Imm, SDS
Corticotropin Releasing Hormone (CRH) peptide (Ovalbumin)CRH Reactivity: Human Host: Synthetic WB, Imm, SDS
Corticotropin Releasing Hormone (CRH) peptide (Ovalbumin)CRH Reactivity: Rat Host: Synthetic WB, Imm, SDS
Corticotropin Releasing Hormone (CRH) peptide (Ovalbumin)CRH Reactivity: Human Host: Synthetic WB, Imm, SDS
Corticotropin Releasing Hormone (CRH) peptide (Ovalbumin)CRH Reactivity: Mouse Host: Synthetic WB, Imm, SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CRH (Corticotropin Releasing Hormone (CRH))
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Background
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Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.
Alias Symbols: CRF
Protein Size: 196 -
Molecular Weight
- 21 kDa
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Gene ID
- 1392
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NCBI Accession
- NM_000756, NP_000747
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UniProt
- P06850
Target
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