G-Protein Signaling Modulator 2 (GPSM2) (N-Term) Peptide
Quick Overview for G-Protein Signaling Modulator 2 (GPSM2) (N-Term) Peptide (ABIN2184309)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Sequence
- SGNLGNTLKV LGNFDEAIVC CQRHLDISRE LNDKVGEARA LYNLGNVYHA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-GPSM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
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Background
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The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).
Alias Symbols: CMCS, DFNB82, LGN, PINS
Protein Size: 684 -
Molecular Weight
- 75 kDa
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Gene ID
- 29899
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NCBI Accession
- NM_013296, NP_037428
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UniProt
- P81274
Target
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