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G-Protein Signaling Modulator 2 (GPSM2) (N-Term) Peptide

GPSM2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2184309
  • Target See all GPSM2 products
    GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 4
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    SGNLGNTLKV LGNFDEAIVC CQRHLDISRE LNDKVGEARA LYNLGNVYHA
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-GPSM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))
    Synonyms
    CMCS Peptide, DFNB82 Peptide, LGN Peptide, PINS Peptide, dfnb82 Peptide, lgn Peptide, pins Peptide, RGD1560967 Peptide, Pinsa Peptide, zgc:63574 Peptide, 6230410J09Rik Peptide, Pins Peptide, G protein signaling modulator 2 Peptide, G-protein signaling modulator 2 S homeolog Peptide, G-protein signaling modulator 2 Peptide, G-protein signalling modulator 2 (AGS3-like, C. elegans) Peptide, GPSM2 Peptide, gpsm2.S Peptide, Gpsm2 Peptide, gpsm2 Peptide
    Background
    The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).

    Alias Symbols: CMCS, DFNB82, LGN, PINS

    Protein Size: 684
    Molecular Weight
    75 kDa
    Gene ID
    29899
    NCBI Accession
    NM_013296, NP_037428
    UniProt
    P81274
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