V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (C-Term) Peptide
MYB
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2184526
Quick Overview for V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB) (C-Term) Peptide (ABIN2184526)
Target
MYB
(V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- VPKNRSLASP LQPCSSTWEP ASCGKMEEQM TSSSQARKYV NAFSARTLVM
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MYB Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
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Background
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This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
Alias Symbols: Cmyb, c-myb, c-myb_CDS, efg
Protein Size: 640 -
Molecular Weight
- 70 kDa
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Gene ID
- 4602
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NCBI Accession
- NM_005375, NP_005366
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UniProt
- P10242
Target
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