Regulator of G-Protein Signaling 17 (RGS17) (C-Term) Peptide
RGS17
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2184821
Quick Overview for Regulator of G-Protein Signaling 17 (RGS17) (C-Term) Peptide (ABIN2184821)
Target
RGS17
(Regulator of G-Protein Signaling 17 (RGS17))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- C-Term
-
Sequence
- NRNLLDPNPH MYEDAQLQIY TLMHRDSFPR FLNSQIYKSF VESTAGSSSE
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-RGS17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeat freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- RGS17 (Regulator of G-Protein Signaling 17 (RGS17))
-
Background
-
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
Alias Symbols: RGS-17, RGSZ2, hRGS17
Protein Size: 210 -
Molecular Weight
- 23 kDa
-
Gene ID
- 26575
-
NCBI Accession
- NM_012419, NP_036551
-
UniProt
- Q9UGC6
Target
-
You are here:
