Diacylglycerol O-Acyltransferase 1 (DGAT1) (N-Term) Peptide
DGAT1
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
Catalog No. ABIN2184872
Quick Overview for Diacylglycerol O-Acyltransferase 1 (DGAT1) (N-Term) Peptide (ABIN2184872)
Target
DGAT1
(Diacylglycerol O-Acyltransferase 1 (DGAT1))
Origin
Human, Mouse
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- HRLQDSLFSS DSGFSNYRGI LNWCVVMLIL SNARLFLENL IKYGILVDPI
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Dgat1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Diacylglycerol O-Acyltransferase 1 (DGAT1) peptide
DGAT1 Reactivity: Human, Mouse, Rat, Dog Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
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Background
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Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. It may be involved in VLDL (very low density lipoprotein) assembly. In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Alias Symbols: C75990, D15Ertd23e, Dgat
Protein Size: 498 -
Molecular Weight
- 57 kDa
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Gene ID
- 13350
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NCBI Accession
- NM_010046, NP_034176
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UniProt
- Q9Z2A7
Target
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