alpha-Fetoprotein (AFP) (C-Term) Peptide
AFP
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2185195
Quick Overview for alpha-Fetoprotein (AFP) (C-Term) Peptide (ABIN2185195)
Target
alpha Fetoprotein (AFP)
(alpha-Fetoprotein (AFP))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- KPQITEEQLE AVIADFSGLL EKCCQGQEQE VCFAEEGQKL ISKTRAALGV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-AFP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- alpha Fetoprotein (AFP) (alpha-Fetoprotein (AFP))
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Background
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This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.
Alias Symbols: FETA, HPAFP
Protein Size: 609 -
Molecular Weight
- 66 kDa
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Gene ID
- 174
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NCBI Accession
- NM_001134, NP_001125
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UniProt
- P02771
Target
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