Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) (N-Term) Peptide
ARNT2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2185576
$160.46
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100 μg
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United States
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Quick Overview for Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) (N-Term) Peptide (ABIN2185576)
Target
ARNT2
(Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- VTLPVAPMAA TGQVRMAGAM PARGGKRRSG MDFDDEDGEG PSKFSRENHS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARNT2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Purification
- Purified
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Concentration
- 1 mg/mL
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Buffer
- Final peptide concentration is 1 mg/mL in PBS.
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Handling Advice
- Avoid repeat freeze-thaw cycles.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))
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Background
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This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
Protein Size: 217 -
Molecular Weight
- 23 kDa
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Gene ID
- 9915
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UniProt
- Q86TN1
Target
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