Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2) (N-Term) Peptide
ARNT2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ARNT2 products
- ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VTLPVAPMAA TGQVRMAGAM PARGGKRRSG MDFDDEDGEG PSKFSRENHS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARNT2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))
- Background
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This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
Protein Size: 217 - Molecular Weight
- 23 kDa
- Gene ID
- 9915
- UniProt
- Q86TN1
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