phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) Peptide
PLCB1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5510838
Quick Overview for phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1) Peptide (ABIN5510838)
Target
Phospholipase C beta 1 (PLCB1)
(phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-PLCB antibody (Catalog #: ARP74371_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Phospholipase C beta 1 (PLCB1) (phospholipase C, beta 1 (phosphoinositide-Specific) (PLCB1))
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Background
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This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Protein Size: 278 -
Molecular Weight
- 30 kDa
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Gene ID
- 10555
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NCBI Accession
- NP_006403
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UniProt
- O15120
Target
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