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A Kinase (PRKA) Anchor Protein 12 (AKAP12) (Middle Region) Peptide

AKAP12 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5510916
  • Target See all AKAP12 products
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MLSSQERMKV QGSPLKKLFT STGLKKLSGK KQKGKRGGGD EESGEHTQVP
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- AKAP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    Background
    The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.

    Alias Symbols: SSeCKS, AKAP250

    Protein Size: 1684
    Gene ID
    9590
    NCBI Accession
    NM_005100, NP_005091
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