A Kinase (PRKA) Anchor Protein 12 (AKAP12) (Middle Region) Peptide
AKAP12
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AKAP12 products
- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MLSSQERMKV QGSPLKKLFT STGLKKLSGK KQKGKRGGGD EESGEHTQVP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- AKAP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
- Background
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: SSeCKS, AKAP250
Protein Size: 1684 - Gene ID
- 9590
- NCBI Accession
- NM_005100, NP_005091
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