A Kinase (PRKA) Anchor Protein 12 (AKAP12) (Middle Region) Peptide
AKAP12
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5510916
Quick Overview for A Kinase (PRKA) Anchor Protein 12 (AKAP12) (Middle Region) Peptide (ABIN5510916)
Target
AKAP12
(A Kinase (PRKA) Anchor Protein 12 (AKAP12))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- MLSSQERMKV QGSPLKKLFT STGLKKLSGK KQKGKRGGGD EESGEHTQVP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- AKAP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
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Background
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: SSeCKS, AKAP250
Protein Size: 1684 -
Gene ID
- 9590
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NCBI Accession
- NM_005100, NP_005091
Target
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