Activating Transcription Factor 2 (ATF2) (C-Term) Peptide
ATF2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5510944
Quick Overview for Activating Transcription Factor 2 (ATF2) (C-Term) Peptide (ABIN5510944)
Target
ATF2
(Activating Transcription Factor 2 (ATF2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- PVTAMQKKSG YHTADKDDSS EDISVPSSPH TEAIQHSSVS TSNGVSSTSK
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Activating Transcription Factor 2 (ATF2) peptide
ATF2 Reactivity: Human, Rat, Cow, Dog Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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Background
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This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. The encoded protein may also be involved in cell's DNA damage response independent of its role in transcriptional regulation. Several alternatively spliced transcript variants have been found for this gene.
Alias Symbols: ATF2,CREB2, CREBP1,
Protein Size: 487 -
Gene ID
- 1386
Target
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