Bone Morphogenetic Protein Receptor 1A (BMPR1A) (N-Term) Peptide
BMPR1A
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5510994
Quick Overview for Bone Morphogenetic Protein Receptor 1A (BMPR1A) (N-Term) Peptide (ABIN5510994)
Target
BMPR1A
(Bone Morphogenetic Protein Receptor 1A (BMPR1A))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GMKSDSDQKK SENGVTLAPE DTLPFLKCYC SGHCPDDAIN NTCITNGHCF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-BMPR1A Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Bone Morphogenetic Protein Receptor 1A (BMPR1A) peptide
BMPR1A Reactivity: Human, Dog Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))
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Background
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The bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.
Alias Symbols: BMPR1A,ACVRLK3,ALK3,
Protein Size: 532 -
Gene ID
- 657
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NCBI Accession
- XP_005270121
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UniProt
- P36894
Target
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