Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptide
CARD11
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511030
Quick Overview for Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptide (ABIN5511030)
Target
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CARD11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Caspase Recruitment Domain Family, Member 11 (CARD11) peptide
CARD11 Reactivity: Human, Mouse, Cow, Dog Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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Background
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The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1
Protein Size: 1171 -
Gene ID
- 84433
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NCBI Accession
- NM_032415, NP_115791
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UniProt
- Q8TES3
Target
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