Caspase Recruitment Domain Family, Member 8 (CARD8) (N-Term) Peptide
CARD8
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511031
$160.46
Plus shipping costs $50.00
100 μg
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United States
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Quick Overview for Caspase Recruitment Domain Family, Member 8 (CARD8) (N-Term) Peptide (ABIN5511031)
Target
CARD8
(Caspase Recruitment Domain Family, Member 8 (CARD8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LGGTFPGDIC SEENQIVSSY ASKVCFEIEE DYKNRQFLGP EGNVDVELID
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-CARD8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARD8 (Caspase Recruitment Domain Family, Member 8 (CARD8))
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Background
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The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene.
Protein Size: 286 -
Gene ID
- 22900
Target
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