Tripeptidyl Peptidase I (TPP1) (C-Term) Peptide
TPP1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511099
Quick Overview for Tripeptidyl Peptidase I (TPP1) (C-Term) Peptide (ABIN5511099)
Target
TPP1
(Tripeptidyl Peptidase I (TPP1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- QHGAGLFDVT RGCHESCLDE EVEGQGFCSG PGWDPVTGWG TPNFPALLKT
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- TPP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TPP1 (Tripeptidyl Peptidase I (TPP1))
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Background
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This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Alias Symbols: CLN2, GIG1, LPIC, SCAR7, TPP-1
Protein Size: 563 -
Gene ID
- 1200
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NCBI Accession
- NM_000391, NP_000382
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UniProt
- O14773
Target
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