DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (Middle Region) Peptide
DGCR8
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511126
Quick Overview for DiGeorge Syndrome Critical Region Gene 8 (DGCR8) (Middle Region) Peptide (ABIN5511126)
Target
DGCR8
(DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- TEEKYGGDSD HPSDGETSVQ PMMTKIKTVL KSRGRPPTEP LPDGWIMTFH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-DGCR8 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DGCR8 (DiGeorge Syndrome Critical Region Gene 8 (DGCR8))
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Background
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This gene encodes a subunit of the microprocessor complex which mediates the biogenesis of microRNAs from the primary microRNA transcript. The encoded protein is a double-stranded RNA binding protein that functions as the non-catalytic subunit of the microprocessor complex. This protein is required for binding the double-stranded RNA substrate and facilitates cleavage of the RNA by the ribonuclease III protein, Drosha. Alternate splicing results in multiple transcript variants.
Alias Symbols: DGCR8,C22orf12, DGCRK6,LP4941,
Protein Size: 773 -
Gene ID
- 54487
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NCBI Accession
- NP_073557
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UniProt
- Q8WYQ5
Target
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