Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) (N-Term) Peptide
LZTS1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511174
Quick Overview for Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1) (N-Term) Peptide (ABIN5511174)
Target
LZTS1
(Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LKKLNRYSDG LLRFGFSQDS GHGKSSSKMG KSEDFFYIKV SQKARGSHHP
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-LZTS1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- LZTS1 (Leucine Zipper, Putative Tumor Suppressor 1 (LZTS1))
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Background
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This gene encodes a tumor suppressor protein that is ubiquitously expressed in normal tissues. In uveal melanomas, expression of this protein is silenced in rapidly metastasizing and metastatic tumor cells but has normal expression in slowly metastasizing or nonmetastasizing tumor cells. This protein may have a role in cell-cycle control by interacting with the Cdk1/cyclinB1 complex. This gene is located on chromosomal region 8p22. Loss of heterozygosity (LOH) in the 8p arm is a common characteristic of many types of cancer.
Alias Symbols: LZTS1, FEZ1,
Protein Size: 596 -
Gene ID
- 11178
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NCBI Accession
- XP_005273451
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UniProt
- Q9Y250
Target
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