Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (N-Term) Peptide
GAD2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511222
Quick Overview for Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (N-Term) Peptide (ABIN5511222)
Target
GAD65 (GAD2)
(Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- FGSEDGSGDS ENPGTARAWC QVAQKFTGGI GNKLCALLYG DAEKPAESGG
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-DCE2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- GAD65 (GAD2) (Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2))
-
Background
-
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Alias Symbols: GAD2,GAD65,
Protein Size: 585 -
Gene ID
- 2572
-
NCBI Accession
- NP_001127838
-
UniProt
- Q05329
Target
-
You are here:
