Integrator Complex Subunit 12 (INTS12) (C-Term) Peptide
Quick Overview for Integrator Complex Subunit 12 (INTS12) (C-Term) Peptide (ABIN5511303)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- SGNGNSATAG PTGSITSKTT SETSSSTSAS LKGPTSQESQ LNAMKRLQMV
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-Ints12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- INTS12 (Integrator Complex Subunit 12 (INTS12))
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Background
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Ints12 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
Alias Symbols: Phf22
Protein Size: 461 -
Gene ID
- 295448
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NCBI Accession
- NM_001007640, NP_001007641
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UniProt
- Q68FR3
Target
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