Myeloid Differentiation Primary Response Gene (88) (MYD88) (Middle Region) Peptide
MYD88
Reactivity: Human
Host: Synthetic
BP, WB
Quick Overview for Myeloid Differentiation Primary Response Gene (88) (MYD88) (Middle Region) Peptide (ABIN5511360)
Target
MYD88
(Myeloid Differentiation Primary Response Gene (88) (MYD88))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- AEEMDFEYLE IRQLETQADP TGRLLDAWQG RPGASVGRLL ELLTKLGRDD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-MYD88 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Myeloid Differentiation Primary Response Gene (88) (MYD88) peptide
MYD88 Reactivity: Human, Mouse, Rat, Dog Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MYD88 (Myeloid Differentiation Primary Response Gene (88) (MYD88))
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Background
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This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.
Alias Symbols: MYD88,
Protein Size: 251 -
Gene ID
- 4615
Target
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