Neuronal Pentraxin II (NPTX2) (Middle Region) Peptide
NPTX2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511396
Quick Overview for Neuronal Pentraxin II (NPTX2) (Middle Region) Peptide (ABIN5511396)
Target
NPTX2
(Neuronal Pentraxin II (NPTX2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- GAQREAIREL TGKLARCEGL AGGKARGAGA TGKDTMGDLP RDPGHVVEQL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- NPTX2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NPTX2 (Neuronal Pentraxin II (NPTX2))
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Background
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This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.
Alias Symbols: NP2, NARP, NP-II
Protein Size: 431 -
Gene ID
- 4885
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NCBI Accession
- NM_002523, NP_002514
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UniProt
- P47972
Target
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