OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Peptide
OTUB1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511414
Quick Overview for OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) Peptide (ABIN5511414)
Target
OTUB1
(OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-OTUB1 antibody (Catalog #: ARP59280_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1) peptide
OTUB1 Reactivity: Human, Mouse, Cow, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))
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Background
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The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.
Alias Symbols: OTB1, OTU1
Protein Size: 271 -
Molecular Weight
- 29 kDa
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Gene ID
- 55611
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NCBI Accession
- NP_060140
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UniProt
- Q96FW1
Target
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