Paraoxonase 2 (PON2) (Middle Region) Peptide
PON2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511445
Quick Overview for Paraoxonase 2 (PON2) (Middle Region) Peptide (ABIN5511445)
Target
PON2
(Paraoxonase 2 (PON2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- LDTLVDNLSI DPSSGDIWVG CHPNGQKLFV YDPNNPPSSE VLRIQNILCE
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- PON2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PON2 (Paraoxonase 2 (PON2))
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Background
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This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones, important bacterial quorum-sensing mediators, suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes. Alternatively spliced transcript variants encoding different isoforms have been described.
Protein Size: 354 -
Gene ID
- 5445
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NCBI Accession
- NM_000305, NP_000296
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UniProt
- Q15165
Target
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