RAB21, Member RAS Oncogene Family (RAB21) (Middle Region) Peptide
Quick Overview for RAB21, Member RAS Oncogene Family (RAB21) (Middle Region) Peptide (ABIN5511483)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- EAESYAESVG AKHYHTSAKQ NKGIEELFLD LCKRMIETAQ VDERAKGNGS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- RAB21 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RAB21 (RAB21, Member RAS Oncogene Family (RAB21))
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Background
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This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues.
Protein Size: 225 -
Gene ID
- 23011
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NCBI Accession
- NM_014999, NP_055814
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UniProt
- Q9UL25
Target
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