RAS P21 Protein Activator 3 (RASA3) (N-Term) Peptide
RASA3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RASA3 products
- RASA3 (RAS P21 Protein Activator 3 (RASA3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YEAWYFLQPR DNGSKSLKPD DLGSLRLNVV YTEDHVFSSD YYSPLRDLLL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RASA3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RASA3 (RAS P21 Protein Activator 3 (RASA3))
- Background
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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
Alias Symbols: RASA3,
Protein Size: 834 - Gene ID
- 22821
- NCBI Accession
- NP_031394
- UniProt
- Q14644
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