RAS P21 Protein Activator 3 (RASA3) (N-Term) Peptide
RASA3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511496
Quick Overview for RAS P21 Protein Activator 3 (RASA3) (N-Term) Peptide (ABIN5511496)
Target
RASA3
(RAS P21 Protein Activator 3 (RASA3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- YEAWYFLQPR DNGSKSLKPD DLGSLRLNVV YTEDHVFSSD YYSPLRDLLL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RASA3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RASA3 (RAS P21 Protein Activator 3 (RASA3))
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Background
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The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. The gene product stimulates the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This family member is an inositol 1,3,4,5-tetrakisphosphate-binding protein, like the closely related RAS p21 protein activator 2. The two family members have distinct pleckstrin-homology domains, with this particular member having a domain consistent with its localization to the plasma membrane.
Alias Symbols: RASA3,
Protein Size: 834 -
Gene ID
- 22821
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NCBI Accession
- NP_031394
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UniProt
- Q14644
Target
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