Vascular Endothelial Growth Factor A (VEGFA) (C-Term) Peptide
VEGFA
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511623
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
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Quick Overview for Vascular Endothelial Growth Factor A (VEGFA) (C-Term) Peptide (ABIN5511623)
Target
VEGFA
(Vascular Endothelial Growth Factor A (VEGFA))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- ECRPKKDRAR QEKKSVRGKG KGQKRKRKKS RYKSWSVYVG ARCCLMPWSL
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-VEGFA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
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Background
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This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Alias Symbols: Name=VEGFA,
Protein Size: 327 -
Gene ID
- 7422
Target
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