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Wilms Tumor 1 (WT1) (N-Term) Peptide

WT1 Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN5511631

Quick Overview for Wilms Tumor 1 (WT1) (N-Term) Peptide (ABIN5511631)

Target

WT1 (Wilms Tumor 1 (WT1))

Origin

Human

Source

  • 10
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Protein Region

    N-Term

    Sequence

    DFAPPGASAY GSLGGPAPPP APPPPPPPPP HSFIKQEPSW GGAEPHEEQC

    Characteristics

    This is a synthetic peptide designed for use in combination with anti-WT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes

    Optimal working dilution should be determined by the investigator.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    WT1 (Wilms Tumor 1 (WT1))

    Background

    WT1 is a transcription factor that contains four zinc-finger motifs at the C-terminus and a proline/glutamine-rich DNA-binding domain at the N-terminus. It has an essential role in the normal development of the urogenital system, and it is mutated in a small subset of patients with Wilm's tumors. Multiple transcript variants, resulting from alternative splicing at two coding exons, have been well characterized. There is also evidence for the use of non-AUG (CUG) translation initiation site upstream of, and in-frame with the first AUG, leading to additional isoforms.

    Protein Size: 432

    Gene ID

    7490
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