Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G) (N-Term) Peptide
IDH3G
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5511695
$160.46
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100 μg
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Quick Overview for Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G) (N-Term) Peptide (ABIN5511695)
Target
IDH3G
(Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- CRPWEVLGAH EVPSRNIFSE QTIPPSAKYG GRHTVTMIPG DGIGPELMLH
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-IDH3G Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- IDH3G (Isocitrate Dehydrogenase 3 (NAD+) gamma (IDH3G))
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Background
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Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the gamma subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. This gene is a candidate gene for periventricular heterotopia. Several alternatively spliced transcript variants of this gene have been described, but only some of their full length natures have been determined.
Alias Symbols: IDH3G,
Protein Size: 393 -
Gene ID
- 3421
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UniProt
- P51553
Target
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